In 1972 a Columbus, Ohio physician, Dr. Philip K. Wood, who devoted his career to the treatment and rehabilitation of people with disabilities, was aware of the talent, capabilities, determination, and courage of those living with a disability. This physician established Ms. Wheelchair America as a forum for the promotion of the achievements, as well as the needs of the people who utilize a wheelchair. There are events currently held in over 30 states throughout the United States. These non-profit organizations are staffed by volunteers throughout the country dedicated to increasing public awareness so that all of its citizens will be able to lead productive and meaningful lives.

The Ms. Wheelchair Pennsylvania Organization has had several state coordinators in the past. In 2017, Pennsylvania hosted the national competition in Erie to crown Ms. Wheelchair Pennsylvania 2018.

The Ms. Wheelchair Pennsylvania Organization is currently based out of Johnstown, PA since September 2019.